Early diagnosis is associated with improved clinical outcomes in benign...
AbstractBackgroundTime of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study...
View ArticleScaling exponents of step-reinforced random walks
AbstractLet \(X_1, X_2, \ldots \) be i.i.d. copies of some real random variable X. For any deterministic \(\varepsilon _2, \varepsilon _3, \ldots \) in \(\{0,1\}\), a basic algorithm introduced by H.A....
View ArticleMethods for conducting international Delphi surveys to optimise global...
AbstractBackgroundCore outcome sets (COS) should be relevant to key stakeholders and widely applicable and usable. Ideally, they are developed for international use to allow optimal data synthesis from...
View ArticlePeritumoral B cells drive proangiogenic responses in HMGB1-enriched...
AbstractSeveral B-cell subsets with distinct functions and polarized cytokine profiles that extend beyond antibody production have been reported in different cancers. Here we have demonstrated that...
View ArticleDocetaxel, Cisplatin, and 5-FU Triplet Therapy as Conversion Therapy for...
AbstractBackgroundThe standard treatment for locoregionally advanced unresectable esophageal squamous cell carcinoma was radical chemoradiotherapy. However, the prognosis was modest. Emerging evidence...
View ArticleTransgastric Single-Incision Laparoscopic Resection for a Gastric Submucosal...
AbstractIntroductionSurgical treatment of gastric submucosal tumors (SMTs) located near the gastroesophageal junction can be technically challenging, especially regarding preservation of the integrity...
View ArticleEsophageal Squamous Cell Cancer: Pathogenesis and Epidemiology
AbstractEsophageal cancer is a highly lethal disease. Despite an increasing incidence of adenocarcinoma in last decades, squamous cell carcinoma remains the predominant cell type worldwide. The...
View ArticleMcKeown Esophagectomy
AbstractThe classical three-phase esophagectomy was described by McKeown in 1976. It is widely adopted in centers worldwide for the treatment of esophageal carcinoma. Since its inception, surgeons have...
View ArticleClonal relationship and alcohol consumption-associated mutational signature...
AbstractBackgroundThe patients with dual oesophageal squamous cell carcinoma (ESCC) and hypopharyngeal cancer (HPC) have poor prognosis; their underlying genetic pathogenesis is unclear. We hypothesise...
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